Unveiling the Differential Impact of Diabetes on Maxillofacial Space Infection Spread and Progression: A Comparative Analysis
DOI:
https://doi.org/10.52783/jns.v14.2714Keywords:
Diabetes, Maxillofacial Infections, Infection Spread, Glycemic Control, Microbial PathogensAbstract
Introduction: This study compared head and neck infection characteristics between diabetic and non-diabetic patients. We investigated the spread of infection, causative pathogens, glycemic control, and comorbidities.
Methods: A study was conducted on 48 patients with maxillofacial infections, comparing those with and without diabetes. Febrile status, blood work, pathogen identification, and antibiotic sensitivities were analysed.
Results: Diabetics exhibited significantly greater spread of infection. Streptococcus, Staphylococcus, and Klebsiella were prevalent in both groups. Comorbidity rates were similar. Diabetics had higher HbA1c and random blood sugar.
Conclusion: Diabetes significantly increases the spread of head and neck infections. Prompt treatment and optimization of glycaemic control are crucial for these patients. Further research should explore comorbidity influences.
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Topazian RG, Goldberg MH, Hupp JR. Oral and maxillofacial infections: Elsevier Health Sciences; 2002.
Nagendrababu, V., Pulikkotil, S. J., Suresh, A., Veettil, S. K., Bhatia, S., & Setzer, F. C. (2019). Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta‐analysis of randomized clinical trials. International Endodontic Journal, 52(6), 779-789.
Ylijoki S, Suuronen R, Jousimies-Somer H. Meurman JH, Lindqvist C. Differences between patients with or without the need for intensive care due to severe odontogenic infections. Journal of oral and maxillofacial surgery. 2001;59(8):867-72.
Ren Y-F, Malmstrom HS. Rapid quantitative determination of C-reactive protein at chair side in dental emergency patients. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology.2007;104(1):49-55.
Kumar, A., Pasha, Z., Salam, S., Aruna, V., Kashwani, R., Sachdeva, K., & Bhagat, N. (2024). Innovative use of a double Y-shaped miniplate in complex mandibular fracture: A rare case report. Community Practitioner, 21(7), 1-8.
Shah BR, Hux JE. Quantifying the risk of infectious diseases for people with diabetes. Diabetes care. 2003;26(2):510-3.
Zheng L, Yang C, Kim E, Zhang W, Cai X, Jiang B, et al. The clinical features of severe multi-space infections of the head and neck in patients with diabetes mellitus compared to non-diabetic patients. British Journal of Oral and Maxillofacial Surgery. 2012;50(8):757-61.
Huang T-T, Tseng F-Y, Liu T-C, Hsu C-J, Chen Y-8, Deep neck infection in diabetic patients: comparison of clinical picture and outcomes with a non-diabetic patients. Otolaryngology-Head and Neck Surgery2005;132(6):943-7.
Kamat RD, Dhupar V, Akkara F, Shetye O. A comparative analysis of9.odontogenic maxillofacial infections in diabetic and nondiabetic patients: an institutional study. Journal of the Korean Association of Oral and Maxillofacial Surgeons. 2015;41(4):176.
Hawkey P. Mechanisms of resistance to antibiotics. Intensive care medicine. 2000;26:S9.
Rega AJ, Aziz SR, Ziccardi VB. Microbiology and antibiotic sensitivities of head and neck space infections of odontogenic origin. Journal of oral and maxillofacial surgery. 2006;64(9):1377-80.
Bryan CS, Reynolds KL, Metzger WT. Bacteremia in diabetic patients: comparison of incidence and mortality with nondiabetic patients. Diabetes care. 1985;8(3):244-9.
Krishnan V, Johnson JV, Helfrick JF. Management of maxillofacial infections: a review of 50 cases. Journal of oral and maxillofacial surgery.1993;51(8):868-73.
Stephenson Jr E, Haug RH, Murphy TA. Management of the diabetic oral and maxillofacial surgery patient. Journal of oral and maxillofacial surgery. 1995;53(2):175-82.
Peters ES, Fong B, Wormuth DW, Sonis ST. Risk factors affecting hospital length of stay in patients with odontogenic maxillofacial infections. Journal of Oral and Maxillofacial surgery. 1996;54(12):1386-91.
Chen M-K, Wen Y-S, Chang C-C, Lee H-S, Huang M-T, Hsiao H-C. Deep neck infections in diabetic patients. American journal of otolaryngology2000;21(3):169-73.
McManus LM, Bloodworth RC, Prihoda TJ, Blodgett JL, Pinckard RN.Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyper-glycemia. Journal of Leukocyte Biology. 2001;70(3):395404.
Storoe W, Haug RH, Lillich TT. The changing face of odontogenic infections. Journal of Oral and Maxillofacial surgery. 2001;59(7):739-48.
Brook I, editor Antibiotic resistance of oral anaerobic bacteria and their effect on the management of upper respiratory tract and head and neck infections. Seminars in respiratory infections; 2002.
Wang J, Ahani A, Pogrel M. A five-year retrospective study of odontogenic maxillofacial infections in a large urban public hospital. International journal of oral and maxillofacial surgery. 2005;34(6):646-9.
Chang C-M, Lu F-H, Guo H-R, Ko W-C. Klebsiella pneumoniae fascial space infections of the head and neck in Taiwan: emphasis on diabetic patients and repetitive infections. Journal of Infection. 2005;50(1):34-40.
Boscolo-Rizzo P, Marchiori C, Montolli F. Vaglia A, Da Mosto M neck infections: a constant challenge. ENT. 2006:68(5):259-65.
Marioni G, Rinaldi R, Staffieri C. Marchese-Ragona R. Saia G, StramaR, et al. Deep neck infection with dental origin: analysis of 85 consecutive cases (2000-2006). Acta otolaryngological. 2008;128(2):201-6.24.
Stoeckle M, Kaech C. Trampuz A. Zimmerli W. The role of diabetes mellitus in patients with bloodstream infections. Swiss medical weekly.2008;138(35):512.
Youssef W, D'Innocenzo R. Mehra P. Antibiotic therapy in the management of severe odontogenic infections: a comparison of two treatment regimens. Oral Surgery, Oral Medicine, Oral Pathology. Oral Radiology and Endodontology, 2008;4(106):505.
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