Ayurvedic Approach to Managing Hyperuricemia: A Case Study

Authors

  • Suman Lata
  • Satyendra Kumar Tiwari

DOI:

https://doi.org/10.63682/jns.v14i30S.6930

Keywords:

Ayurveda, Vatarakta, Gout, Hyperuricemia

Abstract

Hyperuricemia is a metabolic disorder that occurs due to elevated serum uric acid levels, a byproduct of purine metabolism. This condition may affect individuals across different age groups and is commonly associated with gout, a form of inflammatory arthritis characterized by intense joint pain. In Ayurvedic literature, such presentations align closely with Vatarakta, a condition arising from the vitiation of Vata and Rakta Doshas.This case involves a 66-year-old male who presented with persistent bilateral knee discomfort, along with severe pain, swelling, and redness localized to the right great toe. The symptoms were present for approximately three years and significantly impacted his mobility and quality of life.He was administered a classical Ayurvedic regimen from April 28, 2024, to May 23, 2024, consisting of Kaishora Guggulu, Samshamani Vati, Kokilakshadi Kwatha, and Sarivadyasava. Over the course of the treatment, notable symptomatic relief was observed. Inflammation, pain, and tenderness gradually subsided, and his serum uric acid levels reduced from 8.50 mg/dl to 5.83 mg/dl.This case highlights the potential of Ayurvedic formulations in effectively managing gouty arthritis, offering both symptomatic relief and biochemical improvement

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Jin M, Yang F, Yang I, Yin Y, Luo JJ, Wang H, Yang XF. Uric acid, hyperuricemia and vascular diseases. Front Biosci (Landmark Ed). 2012;17(2):656–69. Available from: Uric acid, hyperuricemia and vascular diseases - PubMed

Martillo MA, Nazzal L, Crittenden DB. The crystallization of monosodium urate. Curr Rheumatol Rep. 2014 Feb;16(2):400. Available from:The crystallization of monosodium urate - PubMed

Safiri S, Kolahi AA, Cross M, Carson-Chahhoud K, Hoy D, Almasi-Hashiani A, et al. Prevalence, incidence, and years lived with disability due to gout and its attributable risk factors across 195 countries and territories (1990–2017): a systematic review from the Global Burden of Disease Study 2017. Arthritis Rheumatol. 2020 Nov;72(11):1916–27. Available from:Prevalence, Incidence, and Years Lived With Disability Due to Gout and Its Attributable Risk Factors for 195 Countries and Territories 1990-2017: A Systematic Analysis of the Global Burden of Disease Study 2017 - PubMed

Singh JA, Gaffo A. Gout: epidemiology and associated comorbidities. Semin Arthritis Rheum. 2020;50(3S):S11–S16.Available from: Gout epidemiology and comorbidities - PubMed

Tripathi Bramhanand (editor). Charak Samhita of Charak, Charak Chandrika Hindi Commentary, Chapter 5, verse no.12. 2nd edition. Varanasi; Chaukhambha Surbharati Prakasan; 2005; 986.

Tripathi I, Tripathi DS (editor). Yogaratnakara, Vaidyaprabha Hindi Commentary. Varanasi: Chaukhambha Krishnadas Academy; Reprint 2013. p. 444.

Tripathi I, Tripathi DS. Yogaratnakara, Vaidyaprabha Hindi Commentary. Varanasi: Chaukhambha Krishnadas Academy; Reprint 2013. p. 443.

Shastri A, Shastri RD. Bhaishajya Ratnavali, Vidhyotini Hindi Commentary. Varanasi: Chaukhambha Sanskrit Sansthan; 15th Reprint 2002. p. 525.

Ramachandran AP, Prasad SM, Prasad UN, Jonah S. A comparative study of Kaishora Guggulu and Amrita Guggulu in the management of Utthana Vatarakta. Ayu. 2010 Oct;31(4):410–6.Available from: A comparative study of Kaishora Guggulu and Amrita Guggulu in the management of Utthana Vatarakta - PubMed

Becker MA, Schumacher HR Jr, Wortmann RL, MacDonald PA, Eustace D, Palo WA, et al. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med. 2005 Dec 8;353(23):2450–61. Available from:- Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout | New England Journal of Medicine

Lather A, Gupta V, Bansal P, Sahu M, Sachdeva K, Ghaiye P. A review of the Ayurvedic polyherbal formulation Kaishore Guggulu. Int J Pharm Biol Arch. 2011;2(1):497–503. Available from: (PDF) An Ayurvedic Polyherbal Formulation Kaishore Guggulu: A Review

Usharani P, Nutalapati C, Pokuri VK, Kumar CU, Taduri G. A randomized, double-blind, placebo-controlled clinical study assessing the efficacy and safety of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in hyperuricemia. Clin Pharmacol. 2016;8:51–59.Available from: A randomized, double-blind, placebo-, and positive-controlled clinical pilot study to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with hyperuricemia - PubMed

Sunila ES, Kuttan G. Immunomodulatory and antitumor properties of Piper longum Linn. and piperine. J Ethnopharmacol. 2004 Mar;90(2–3):339–46.Available from: Immunomodulatory and antitumor activity of Piper longum Linn. and piperine - PubMed

Khare CP. Indian Medicinal Plants: An Illustrated Dictionary. Berlin/Heidelberg: Springer-Verlag; 2007. p. 733. ISBN: 978-0-387-70637-5.

Kalikar MV, Thawani VR, Varadpande UK, Sontakke SD, Singh RP, Khiyani RK. The immunomodulatory effects of Tinospora cordifolia extract in HIV-positive patients. Indian J Pharmacol. 2008 Jun;40(3):107–10.Available from: Immunomodulatory effect of Tinospora cordifolia extract in human immuno-deficiency virus positive patients - PubMed

Wesley JJ, Christina AJ, Chidambaranathan N. Effects of alcoholic extract of Tinospora cordifolia on acute and subacute inflammation. Pharmacologyonline. 2008;3:683–7. Available from: Anti-inflammatory activity of Guduchi Ghana (aqueous extract of Tinospora Cordifolia Miers.) - PMC

Shastri A, Shastri RD. Bhaishajya Ratnavali, Vidhyotini Hindi Commentary. Varanasi: Chaukhambha Sanskrit Sansthan; 15th Reprint 2002. p. 525.

Mehta C, Bhardwaj A, Bhatia Y, Tripathy BP. A comparative study of Siravyadha and Kokilakshadi Kshayama in Vatarakta with reference to gout. Res Rev J Ayurvedic Sci Yoga Naturopathy. 2017;4(3):6–10. Available from:PDFmedicaljournals.stmjournals.in+1medicaljournals.stmjournals.in+1

Tripathi B. Charak Samhita, Charak Chandrika Hindi Commentary. Varanasi: Chaukhambha Surbharati Prakashan; Reprint 2005. p. 983–1008.

.

Downloads

Published

2025-02-05

How to Cite

1.
Lata S, Kumar Tiwari S. Ayurvedic Approach to Managing Hyperuricemia: A Case Study. J Neonatal Surg [Internet]. 2025Feb.5 [cited 2025Oct.5];14(1S):1285-91. Available from: https://mail.jneonatalsurg.com/index.php/jns/article/view/6930