Anatomical Insights into the Caudate Lobe: Morphological Diversity and Clinical Relevance from a Cadaveric Perspective
Keywords:
Caudate lobe, Morphometry, Hepatic anatomy, Harbin’s Index, Liver morphologyAbstract
Background: The liver, the largest gland of the human body, exhibits significant morphological diversity, especially in its caudate lobe (CL). Due to its independent vascularization and biliary drainage, the CL functions as a distinct anatomical unit, often termed the “third liver.” Variations in its morphology and dimensions are clinically significant in hepatic surgery, radiology, and transplantation.
Materials and Methods: This cross-sectional descriptive study was conducted on 48 formalin-preserved adult human liver specimens obtained from the Department of Anatomy, University College of Medical Sciences, Delhi. Each liver was examined for caudate lobe morphology, including shape, fissures, and notches. Morphometric parameters—transverse and vertical diameters of both caudate and right lobes—were measured using a digital vernier calliper, and the caudate-to-right lobe ratio (Harbin’s Index) was calculated.
Results: The caudate lobe was present in all specimens, with pyriform shape being the most common (67%), followed by rectangular (25%) and irregular (8%). Notches were observed in 38% and vertical fissures in 25% of specimens. The mean transverse and vertical dimensions of the caudate lobe were 30.2 ± 4.8 mm and 57.5 ± 5.3 mm, respectively, with a mean caudate-to-right lobe ratio of 0.14.
Conclusion: The observed morphological diversity and morphometric parameters of the caudate lobe provide vital reference data for surgical and radiological applications. Understanding these variations enhances accuracy in hepatic imaging and surgical interventions, aiding in the diagnosis of caudate lobe hypertrophy and cirrhotic changes..
Downloads
References
Couinaud C. Liver anatomy: portal (and suprahepatic) segmentation. Dig Surg. 1999;16(6):459–467.
Healey JE, Schroy PC. Anatomy of the biliary ducts within the human liver: Analysis of the prevailing pattern of branching and the major variations of the biliary ducts. AMA Arch Surg. 1953;66(5):599–616.
Nagato AC, et al. Anatomical variations of the caudate lobe of the human liver: Morphometric study and clinical implications. Surg Radiol Anat. 2017;39(1):45–52.
Nasu K, et al. Morphological variations of the caudate lobe and their surgical relevance. J Hepatobiliary Pancreat Sci. 2014;21(9):689–696.
Harbin WP, et al. Computed tomography of the caudate lobe: Normal anatomy, variants, and pathology. Radiology. 1980;137(3):661–664.
Ito K, et al. Hypertrophy of the caudate lobe in cirrhosis: Correlation with portal hypertension and liver function. Radiology. 1997;203(2):457–462.
Basile F, et al. Surgical anatomy of the caudate lobe and its implications in liver resection. World J Surg. 2013;37(10):2411–2418.
Joshi SD, et al. Morphological study of the caudate lobe of liver and its clinical implications. J Clin Diagn Res. 2014;8(8):AC01–AC03.
Macchi V, Porzionato A, Parenti A, De Caro R. Morphology and statistical analysis of the caudate lobe of the human liver. Clin Anat. 1997;10(4):253–260.
Kumar N, Patil J, Sujatha N, et al. Morphometric and morphological study of the caudate lobe of the liver in South Indian population. J Clin Diagn Res. 2013;7(2):277–280.
Awaya H, Mitchell DG, Kamiyama T, Holland G, Ito K, Matsumoto T, et al. Cirrhosis: modified caudate-right lobe ratio. Radiology. 2002;224(3):769–774.
Sahni D, Aggarwal A, Kumar A, Singh B. Morphometric study of caudate lobe of liver and its clinical significance. Indian J Gastroenterol. 2016;35(1):40–44.
Chavan S, Kumar V, Singh R. Anatomical variations of the caudate lobe of liver in North Indian population. J Clin Diagn Res. 2017;11(5):AC01–AC04.
Nayak SB, Kumar D, Nayak S, Krishnamurthy A. Morphological variations of the caudate lobe of the liver in adult human cadavers. Anat Sci Int. 2012;87(4):209–214.
Oguz NK, Gunduz D. Assessment of the morphology and morphometry of the caudate lobe of the liver using computed tomography. Eur Rev Med Pharmacol Sci. 2023;27(8):3344–3350.
Ibrahim IH. Morphological variations and measurements of the caudate lobe of the human liver: A cadaveric study. Med J Cairo Univ. 2020;88(1):155–160.
Sarala HS, Jyothilakshmi TK, Shubha R. Morphological variations of caudate lobe of the liver and their clinical implications. Int J Anat Res. 2015;3(2):980–983.
Smith CL, Patel KB, Turner L, Soames RW. Morphology and morphometry of the caudate lobe in two populations: a comparative anatomical study. Anat Sci Int. 2018;93(1):48–57
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.